Nuclear Ca(2)+ and the cAMP Response Element-Binding Protein Family Mediate a Late Phase of Activity-Dependent Neuroprotection

The mechanism by which physiological synaptic NMDA receptor activity promotes neuronal survival is not well understood. Here, we show that that an episode of synaptic activity can promote neuroprotection for a long time after that activity has ceased. This long-lasting or “late phase” of neuroprotec...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Papadia, Sofia, Stevenson, Patrick, Hardingham, Neil R., Bading, Hilmar, Hardingham, Giles E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725111/
https://ncbi.nlm.nih.gov/pubmed/15858054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5019-04.2005
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