Nuclear Ca(2)+ and the cAMP Response Element-Binding Protein Family Mediate a Late Phase of Activity-Dependent Neuroprotection

The mechanism by which physiological synaptic NMDA receptor activity promotes neuronal survival is not well understood. Here, we show that that an episode of synaptic activity can promote neuroprotection for a long time after that activity has ceased. This long-lasting or “late phase” of neuroprotec...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Papadia, Sofia, Stevenson, Patrick, Hardingham, Neil R., Bading, Hilmar, Hardingham, Giles E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2005
Schlagworte:
Cellular/Molecular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725111/
https://ncbi.nlm.nih.gov/pubmed/15858054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5019-04.2005
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