Mice with Genetically Altered Glucocorticoid Receptor Expression Show Altered Sensitivity for Stress-Induced Depressive Reactions

Altered glucocorticoid receptor (GR) signaling is a postulated mechanism for the pathogenesis of major depression. To mimic the human situation of altered GR function claimed for depression, we generated mouse strains that underexpress or overexpress GR, but maintain the regulatory genetic context c...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Ridder, Stephanie, Chourbaji, Sabine, Hellweg, Rainer, Urani, Alexandre, Zacher, Christiane, Schmid, Wolfgang, Zink, Mathias, Hörtnagl, Heide, Flor, Herta, Henn, Fritz A., Schütz, Günther, Gass, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725059/
https://ncbi.nlm.nih.gov/pubmed/15987954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0736-05.2005
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