Glucocorticoid induction of the rat tryptophan oxygenase gene is mediated by two widely separated glucocorticoid-responsive elements.

Transcription of the gene coding for tryptophan oxygenase (TO) in rat liver is induced 10-fold by glucocorticoids. To identify DNA elements mediating the glucocorticoid-regulated expression of the TO gene we transfected mouse L cells with a fusion gene consisting of 1.95 kb TO 5'-flanking sequences...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Danesch, U, Gloss, B, Schmid, W, Schütz, G, Schüle, R, Renkawitz, R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC553443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3582368/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1987.tb04800.x
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