Human Embryonic Stem Cell-Derived Oligodendrocyte Progenitor Cell Transplants Remyelinate and Restore Locomotion after Spinal Cord Injury

Demyelination contributes to loss of function after spinal cord injury, and thus a potential therapeutic strategy involves replacing myelin-forming cells. Here, we show that transplantation of human embryonic stem cell (hESC)-derived oligodendrocyte progenitor cells (OPCs) into adult rat spinal cord...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Keirstead, Hans S., Nistor, Gabriel, Bernal, Giovanna, Totoiu, Minodora, Cloutier, Frank, Sharp, Kelly, Steward, Oswald
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724772/
https://ncbi.nlm.nih.gov/pubmed/15888645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0311-05.2005
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