The desmosome is a mesoscale lipid raft–like membrane domain

Desmogleins (Dsgs) are cadherin family adhesion molecules essential for epidermal integrity. Previous studies have shown that desmogleins associate with lipid rafts, but the significance of this association was not clear. Here, we report that the desmoglein transmembrane domain (TMD) is the primary...

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Udgivet i:Mol Biol Cell
Main Authors: Lewis, Joshua D., Caldara, Amber L., Zimmer, Stephanie E., Stahley, Sara N., Seybold, Anna, Strong, Nicole L., Frangakis, Achilleas S., Levental, Ilya, Wahl, James K., Mattheyses, Alexa L., Sasaki, Takashi, Nakabayashi, Kazuhiko, Hata, Kenichiro, Matsubara, Yoichi, Ishida-Yamamoto, Akemi, Amagai, Masayuki, Kubo, Akiharu, Kowalczyk, Andrew P.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2019
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724694/
https://ncbi.nlm.nih.gov/pubmed/30943110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-10-0649
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