The desmosome is a mesoscale lipid raft–like membrane domain

Desmogleins (Dsgs) are cadherin family adhesion molecules essential for epidermal integrity. Previous studies have shown that desmogleins associate with lipid rafts, but the significance of this association was not clear. Here, we report that the desmoglein transmembrane domain (TMD) is the primary...

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Publicado en:Mol Biol Cell
Main Authors: Lewis, Joshua D., Caldara, Amber L., Zimmer, Stephanie E., Stahley, Sara N., Seybold, Anna, Strong, Nicole L., Frangakis, Achilleas S., Levental, Ilya, Wahl, James K., Mattheyses, Alexa L., Sasaki, Takashi, Nakabayashi, Kazuhiko, Hata, Kenichiro, Matsubara, Yoichi, Ishida-Yamamoto, Akemi, Amagai, Masayuki, Kubo, Akiharu, Kowalczyk, Andrew P.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Cell Biology 2019
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724694/
https://ncbi.nlm.nih.gov/pubmed/30943110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E18-10-0649
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