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Targeting Regulatory T Cells by Addressing Tumor Necrosis Factor and Its Receptors in Allogeneic Hematopoietic Cell Transplantation and Cancer

An intricate network of molecular and cellular actors orchestrates the delicate balance between effector immune responses and immune tolerance. The pleiotropic cytokine tumor necrosis factor-alpha (TNF) proves as a pivotal protagonist promoting but also suppressing immune responses. These opposite a...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Wajant, Harald, Beilhack, Andreas
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724557/
https://ncbi.nlm.nih.gov/pubmed/31555271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02040
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