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Targeting Regulatory T Cells by Addressing Tumor Necrosis Factor and Its Receptors in Allogeneic Hematopoietic Cell Transplantation and Cancer

An intricate network of molecular and cellular actors orchestrates the delicate balance between effector immune responses and immune tolerance. The pleiotropic cytokine tumor necrosis factor-alpha (TNF) proves as a pivotal protagonist promoting but also suppressing immune responses. These opposite a...

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Vydáno v:Front Immunol
Hlavní autoři: Wajant, Harald, Beilhack, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724557/
https://ncbi.nlm.nih.gov/pubmed/31555271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02040
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