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Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with post-infectious, Borrelia burgdorferi-induced Lyme arthritis

In most patients with Lyme arthritis (LA), antibiotic therapy results in Borrelia burgdorferi pathogen elimination, tissue repair, and return to homeostasis. However, despite spirochetal killing, some patients develop proliferative synovitis, characterized by synovial hyperplasia, inflammation, vasc...

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Bibliografiske detaljer
Udgivet i:Cell Microbiol
Main Authors: Lochhead, Robert B., Arvikar, Sheila L., Aversa, John M., Sadreyev, Ruslan I., Strle, Klemen, Steere, Allen C.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724218/
https://ncbi.nlm.nih.gov/pubmed/30218476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12954
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