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Interferon-gamma production in Lyme arthritis synovial tissue promotes differentiation of fibroblast-like synoviocytes into immune effector cells

Lyme arthritis (LA), a late disease manifestation of Borrelia burgdorferi infection, usually resolves with antibiotic therapy. However, some patients develop proliferative synovitis lasting months to several years after spirochetal killing, called post-infectious LA. In this study, we phenotyped hem...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cell Microbiol
Hauptverfasser: Lochhead, Robert B., Ordoñez, David, Arvikar, Sheila L., Aversa, John M., Oh, Luke S., Heyworth, Benton, Sadreyev, Ruslan, Steere, Allen C., Strle, Klemen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336510/
https://ncbi.nlm.nih.gov/pubmed/30550623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cmi.12992
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