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Pharmacokinetic Profile and Anti-Adhesive Effect of Oxaliplatin-PLGA Microparticle-Loaded Hydrogels in Rats for Colorectal Cancer Treatment

Colorectal cancer (CRC) is one of the most malignant and fatal cancers worldwide. Although cytoreductive surgery combined with chemotherapy is considered a promising therapy, peritoneal adhesion causes further complications after surgery. In this study, oxaliplatin-loaded Poly-(d,l-lactide-co-glycol...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Abuzar, Sharif Md, Ahn, Jun-Hyun, Park, Kyung Su, Park, Eun Jung, Baik, Seung Hyuk, Hwang, Sung-Joo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6723418/
https://ncbi.nlm.nih.gov/pubmed/31387217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11080392
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