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Hydrophilic Interaction Liquid Chromatography Coupled to Mass Spectrometry and Multivariate Analysis of the De Novo Pyrimidine Pathway Metabolites

In this study, we describe the optimization of a Hydrophilic Interaction Liquid Chromatography coupled to mass spectrometry (HILIC-MS) method for the evaluation of 14 metabolites related to the de novo synthesis of pyrimidines (dnSP) while using multivariate analysis, which is the metabolic pathway...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Galeano Garcia, Paula, Zimmermann, Barbara H., Carazzone, Chiara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722987/
https://ncbi.nlm.nih.gov/pubmed/31370321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9080328
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