Biomimetic Magnetic Nanocarriers Drive Choline Kinase Alpha Inhibitor inside Cancer Cells for Combined Chemo-Hyperthermia Therapy

Choline kinase α1 (ChoKα1) has become an excellent antitumor target. Among all the inhibitors synthetized, the new compound Ff35 shows an excellent capacity to inhibit ChoKα1 activity. However, soluble Ff35 is also capable of inhibiting choline uptake, making the inhibitor not selective for ChoKα1....

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Pharmaceutics
Главные авторы: Jabalera, Ylenia, Sola-Leyva, Alberto, Peigneux, Ana, Vurro, Federica, Iglesias, Guillermo R., Vilchez-Garcia, Jesus, Pérez-Prieto, Inmaculada, Aguilar-Troyano, Francisco J., López-Cara, Luisa C., Carrasco-Jiménez, María P., Jimenez-Lopez, Concepcion
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722936/
https://ncbi.nlm.nih.gov/pubmed/31408964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics11080408
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы