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Dopamine receptor D(2) activation suppresses the radiosensitizing effect of aripiprazole via activation of AMPK
Drug repositioning has garnered attention as an alternative strategy to the discovery and development of novel anticancer drug candidates. In this study, we screened 321 FDA‐approved drugs against nonirradiated and irradiated MCF‐7 cells, revealing that aripiprazole, a dopamine receptor D2 (D2R) par...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6722896/ https://ncbi.nlm.nih.gov/pubmed/31301124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/2211-5463.12699 |
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