Biotransformation of the Mycotoxin Zearalenone to its Metabolites Hydrolyzed Zearalenone (HZEN) and Decarboxylated Hydrolyzed Zearalenone (DHZEN) Diminishes its Estrogenicity In Vitro and In Vivo

Zearalenone (ZEN)-degrading enzymes are a promising strategy to counteract the negative effects of this mycotoxin in livestock. The reaction products of such enzymes need to be thoroughly characterized before technological application as a feed additive can be envisaged. Here, we evaluated the estro...

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Veröffentlicht in:Toxins (Basel)
Hauptverfasser: Fruhauf, Sebastian, Novak, Barbara, Nagl, Veronika, Hackl, Matthias, Hartinger, Doris, Rainer, Valentina, Labudová, Silvia, Adam, Gerhard, Aleschko, Markus, Moll, Wulf-Dieter, Thamhesl, Michaela, Grenier, Bertrand
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722729/
https://ncbi.nlm.nih.gov/pubmed/31434326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins11080481
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