Tumor Cell-Based Vaccine Generated With High Hydrostatic Pressure Synergizes With Radiotherapy by Generating a Favorable Anti-tumor Immune Microenvironment

Dendritic cell (DC)-based vaccines pulsed with high hydrostatic pressure (HHP)-inactivated tumor cells have been demonstrated to be a promising immunotherapy for solid tumors. We focused on sole injection of tumor cells that were inactivated by HHP and their combination with local radiotherapy (RTx)...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Seitz, Christoph, Rückert, Michael, Deloch, Lisa, Weiss, Eva-Maria, Utz, Sebastian, Izydor, Marika, Ebel, Nina, Schlücker, Eberhard, Fietkau, Rainer, Gaipl, Udo S., Frey, Benjamin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722191/
https://ncbi.nlm.nih.gov/pubmed/31555582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00805
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