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Different effects of knockouts in ALDH2 and ACSS2 on embryonic stem cell differentiation

BACKGROUND: Ethanol (EtOH) is a teratogen that causes severe birth defects, but the mechanisms by which EtOH affects stem cell differentiation are unclear. Our goal here is to examine the effects of EtOH and its metabolites, acetaldehyde (AcH) and acetate, on embryonic stem cell (ESC) differentiatio...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Serio, Ryan N, Lu, Changyuan, Gross, Steven S, Gudas, Lorraine J
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6722009/
https://ncbi.nlm.nih.gov/pubmed/31283017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.14146
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