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Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ
Ethanol (EtOH) is a teratogen, but its teratogenic mechanisms are not fully understood. The alcohol form of vitamin A (retinol/ROL) can be oxidized to all-trans-retinoic acid (RA), which plays a critical role in stem cell differentiation and development. Using an embryonic stem cell (ESC) model to a...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6462535/ https://ncbi.nlm.nih.gov/pubmed/30737277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007153 |
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