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TLR8 ligation induces apoptosis of monocytic myeloid‐derived suppressor cells

Myeloid‐derived suppressor cells (MDSCs) accumulate in tumors and the peripheral blood of cancer patients and demonstrate cancer‐promoting activity across multiple tumor types. A limited number of agents are known to impact MDSC activity. TLR8 is expressed in myeloid cells. We investigated expressio...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Dang, Yushe, Rutnam, Zina J., Dietsch, Gregory, Lu, Hailing, Yang, Yi, Hershberg, Robert, Disis, Mary L.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721845/
https://ncbi.nlm.nih.gov/pubmed/29345064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.5AB0217-070R
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