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Effect of TLR Agonists on the Differentiation and Function of Human Monocytic Myeloid Derived Suppressor Cells

Tumors persist by occupying immunosuppressive microenvironments that inhibit the activity of tumoricidal T and NK cells. Monocytic myeloid-derived suppressor cells (mMDSC) are an important component of this immunosuppressive milieu. We find that the suppressive activity of mMDSC isolated from cancer...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wang, Jing, Shirota, Yuko, Bayik, Defne, Shirota, Hidekazu, Tross, Debra, Gulley, James L., Wood, Lauren, Berzofsky, Jay A., Klinman, Dennis M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402268/
https://ncbi.nlm.nih.gov/pubmed/25825448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402004
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