Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

Hepatitis C virus (HCV) is a highly variable pathogen that frequently establishes chronic infection. This genetic variability is affected by the adaptive immune response but the contribution of other host factors is unclear. Here, we examined the role played by interferon lambda-4 (IFN-λ4) on HCV di...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ansari, M Azim, Aranday-Cortes, Elihu, Ip, Camilla LC, da Silva Filipe, Ana, Lau, Siu Hin, Bamford, Connor, Bonsall, David, Trebes, Amy, Piazza, Paolo, Sreenu, Vattipally, Cowton, Vanessa M, Hudson, Emma, Bowden, Rory, Patel, Arvind H, Foster, Graham R, Irving, William L, Agarwal, Kosh, Thomson, Emma C, Simmonds, Peter, Klenerman, Paul, Holmes, Chris, Barnes, Eleanor, Spencer, Chris CA, McLauchlan, John, Pedergnana, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721795/
https://ncbi.nlm.nih.gov/pubmed/31478835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42463
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