Genome-to-genome analysis highlights the impact of the human innate and adaptive immune systems on the hepatitis C virus

Outcomes of hepatitis C virus (HCV) infection and treatment depend on viral and host genetic factors. We use human genome-wide genotyping arrays and new whole-genome HCV viral sequencing technologies to perform a systematic genome-to-genome study of 542 individuals chronically infected with HCV, pre...

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Bibliografiska uppgifter
I publikationen:Nat Genet
Huvudupphovsmän: Ansari, M. Azim, Pedergnana, Vincent, Ip, Camilla, Magri, Andrea, Von Delft, Annette, Bonsall, David, Chaturvedi, Nimisha, Bartha, Istvan, Smith, David, Nicholson, George, McVean, Gilean, Trebes, Amy, Piazza, Paolo, Fellay, Jacques, Cooke, Graham, Foster, Graham R, Hudson, Emma, McLauchlan, John, Simmonds, Peter, Bowden, Rory, Klenerman, Paul, Barnes, Eleanor, Spencer, Chris C. A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5873514/
https://ncbi.nlm.nih.gov/pubmed/28394351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3835
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