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The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors

Various growth factors and full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this process. Elevated levels of nuclear EGFR correlate with poor prognosis in various cancers. In recent...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cells
Hauptverfasser: Shah, Poonam, Chaumet, Alexandre, Royle, Stephen J., Bard, Frederic A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721735/
https://ncbi.nlm.nih.gov/pubmed/31426451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080915
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