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The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors

Various growth factors and full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this process. Elevated levels of nuclear EGFR correlate with poor prognosis in various cancers. In recent...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Shah, Poonam, Chaumet, Alexandre, Royle, Stephen J., Bard, Frederic A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721735/
https://ncbi.nlm.nih.gov/pubmed/31426451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080915
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