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The NAE Pathway: Autobahn to the Nucleus for Cell Surface Receptors

Various growth factors and full-length cell surface receptors such as EGFR are translocated from the cell surface to the nucleoplasm, baffling cell biologists to the mechanisms and functions of this process. Elevated levels of nuclear EGFR correlate with poor prognosis in various cancers. In recent...

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Vydáno v:Cells
Hlavní autoři: Shah, Poonam, Chaumet, Alexandre, Royle, Stephen J., Bard, Frederic A.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721735/
https://ncbi.nlm.nih.gov/pubmed/31426451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080915
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