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IGF2/IGF1R Signaling as a Therapeutic Target in MYB-Positive Adenoid Cystic Carcinomas and Other Fusion Gene-Driven Tumors

Chromosome rearrangements resulting in pathogenetically important gene fusions are a common feature of many cancers. They are often potent oncogenic drivers and have key functions in central cellular processes and pathways and encode transcription factors, transcriptional co-regulators, growth facto...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Andersson, Mattias K., Åman, Pierre, Stenman, Göran
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721700/
https://ncbi.nlm.nih.gov/pubmed/31426421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080913
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