MicroRNA-34a and MicroRNA-181a Mediate Visfatin-Induced Apoptosis and Oxidative Stress via NF-κB Pathway in Human Osteoarthritic Chondrocytes

Current evidence suggests a complex interaction between adipokines and microRNA (miRNA) in osteoarthritis (OA) pathogenesis. The present study explored the role of miR-34a and miR-181a in regulating apoptosis and oxidative stress induced by visfatin in human OA chondrocytes. Chondrocytes were transf...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Cheleschi, Sara, Tenti, Sara, Mondanelli, Nicola, Corallo, Claudio, Barbarino, Marcella, Giannotti, Stefano, Gallo, Ines, Giordano, Antonio, Fioravanti, Antonella
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721672/
https://ncbi.nlm.nih.gov/pubmed/31405216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8080874
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