MicroRNA Mediate Visfatin and Resistin Induction of Oxidative Stress in Human Osteoarthritic Synovial Fibroblasts Via NF-κB Pathway

Synovial membrane inflammation actively participate to structural damage during osteoarthritis (OA). Adipokines, miRNA, and oxidative stress contribute to synovitis and cartilage destruction in OA. We investigated the relationship between visfatin, resistin and miRNA in oxidative stress regulation,...

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Bibliographic Details
Main Authors: Sara Cheleschi, Ines Gallo, Marcella Barbarino, Stefano Giannotti, Nicola Mondanelli, Antonio Giordano, Sara Tenti, Antonella Fioravanti
Format: Artigo
Language:Inglês
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
microrna
visfatin
resistin
osteoarthritis
oxidative stress
apoptosis
synovial fibroblasts
synovitis
nf-κb
Online Access:https://www.mdpi.com/1422-0067/20/20/5200
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