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The Histone Demethylase Enzymes KDM3A and KDM4B Co-Operatively Regulate Chromatin Transactions of the Estrogen Receptor in Breast Cancer

Many estrogen receptor (ER)-positive breast cancers develop resistance to endocrine therapy but retain canonical receptor signalling in the presence of selective ER antagonists. Numerous co-regulatory proteins, including enzymes that modulate the chromatin environment, control the transcriptional ac...

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Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Jones, Dominic, Wilson, Laura, Thomas, Huw, Gaughan, Luke, Wade, Mark A.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721541/
https://ncbi.nlm.nih.gov/pubmed/31390833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081122
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