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The Histone Demethylase Enzymes KDM3A and KDM4B Co-Operatively Regulate Chromatin Transactions of the Estrogen Receptor in Breast Cancer

Many estrogen receptor (ER)-positive breast cancers develop resistance to endocrine therapy but retain canonical receptor signalling in the presence of selective ER antagonists. Numerous co-regulatory proteins, including enzymes that modulate the chromatin environment, control the transcriptional ac...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Principais autores: Jones, Dominic, Wilson, Laura, Thomas, Huw, Gaughan, Luke, Wade, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721541/
https://ncbi.nlm.nih.gov/pubmed/31390833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081122
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