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Maintenance BEZ235 Treatment Prolongs the Therapeutic Effect of the Combination of BEZ235 and Radiotherapy for Colorectal Cancer

Our previous study demonstrated that administration of NVP-BEZ235 (BEZ235), a dual PI3K/mTOR inhibitor, before radiotherapy (RT) enhanced the radiotherapeutic effect in colorectal cancer (CRC) cells both in vitro and in vivo. Here, we evaluated whether maintenance BEZ235 treatment, after combinatori...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Chen, Yu-Hsuan, Wang, Chun-Wei, Wei, Ming-Feng, Tzeng, Yi-Shin, Lan, Keng-Hsueh, Cheng, Ann-Lii, Kuo, Sung-Hsin
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721476/
https://ncbi.nlm.nih.gov/pubmed/31430901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081204
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