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PD-L1 Blockade by Atezolizumab Downregulates Signaling Pathways Associated with Tumor Growth, Metastasis, and Hypoxia in Human Triple Negative Breast Cancer

Triple negative breast cancer (TNBC) is the most aggressive type of breast cancer, which shows resistance to common breast cancer therapies, as it lacks the expression of the most common breast cancer targets. Therefore, TNBC treatment remains a challenge. Targeting programmed cell death-ligand 1 (P...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Saleh, Reem, Taha, Rowaida Z., Sasidharan Nair, Varun, Alajez, Nehad M., Elkord, Eyad
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721435/
https://ncbi.nlm.nih.gov/pubmed/31349612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11081050
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