Downregulation of exosomal CLEC3B in hepatocellular carcinoma promotes metastasis and angiogenesis via AMPK and VEGF signals

BACKGROUND: C-Type Lectin Domain Family 3 Member B (CLEC3B), is down-regulated in serum and tumor tissues in different cancers including hepatocellular carcinoma (HCC). However, the functions of CLEC3B in HCC remains elucidated. The aim of this study is to analyze the roles of CLEC3B in HCC. METHODS...

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Gepubliceerd in:Cell Commun Signal
Hoofdauteurs: Dai, Wenjuan, Wang, Yilin, Yang, Tianxiao, Wang, Jing, Wu, Weicheng, Gu, Jianxin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2019
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Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6721425/
https://ncbi.nlm.nih.gov/pubmed/31477130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0423-6
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