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Normalizing Plasma Renin Activity in Experimental Dilated Cardiomyopathy: Effects on Edema, Cachexia, and Survival

Heart failure (HF) patients frequently have elevated plasma renin activity. We examined the significance of elevated plasma renin activity in a translationally-relevant model of dilated cardiomyopathy (DCM), which replicates the progressive stages (A–D) of human HF. Female mice with DCM and elevated...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Sullivan, Ryan D., Mehta, Radhika M., Tripathi, Ranjana, Gladysheva, Inna P., Reed, Guy L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720926/
https://ncbi.nlm.nih.gov/pubmed/31404946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20163886
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