Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study

Background: New treatments are needed to reduce myocardial infarct size (MI) and prevent heart failure (HF) following acute myocardial infarction (AMI), which are the leading causes of death and disability worldwide. Studies in rodent AMI models showed that genetic and pharmacological inhibition of...

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Publicado no:Int J Mol Sci
Main Authors: Ong, Sang-Bing, Kwek, Xiu-Yi, Katwadi, Khairunnisa, Hernandez-Resendiz, Sauri, Crespo-Avilan, Gustavo E., Ismail, Nur Izzah, Lin, Ying-Hsi, Yap, En Ping, Lim, Song-Yi, Ja, K P Myu Mai, Ramachandra, Chrishan J.A., Tee, Nicole, Toh, Jin Jiat, Shim, Winston, Wong, Philip, Cabrera-Fuentes, Hector A., Hausenloy, Derek J
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720595/
https://ncbi.nlm.nih.gov/pubmed/31443187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20163972
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