Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study

Background: New treatments are needed to reduce myocardial infarct size (MI) and prevent heart failure (HF) following acute myocardial infarction (AMI), which are the leading causes of death and disability worldwide. Studies in rodent AMI models showed that genetic and pharmacological inhibition of...

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Pubblicato in:Int J Mol Sci
Autori principali: Ong, Sang-Bing, Kwek, Xiu-Yi, Katwadi, Khairunnisa, Hernandez-Resendiz, Sauri, Crespo-Avilan, Gustavo E., Ismail, Nur Izzah, Lin, Ying-Hsi, Yap, En Ping, Lim, Song-Yi, Ja, K P Myu Mai, Ramachandra, Chrishan J.A., Tee, Nicole, Toh, Jin Jiat, Shim, Winston, Wong, Philip, Cabrera-Fuentes, Hector A., Hausenloy, Derek J
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720595/
https://ncbi.nlm.nih.gov/pubmed/31443187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20163972
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