Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation

Epstein-Barr virus (EBV) causes Burkitt, Hodgkin, and post-transplant B cell lymphomas. How EBV remodels metabolic pathways to support rapid B cell outgrowth remains largely unknown. To gain insights, primary human B cells were profiled by tandem-mass-tag-based proteomics at rest and at nine time po...

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Vydáno v:Cell Metab
Hlavní autoři: Wang, Liang Wei, Shen, Hongying, Nobre, Luis, Ersing, Ina, Paulo, Joao A., Trudeau, Stephen, Wang, Zhonghao, Smith, Nicholas A., Ma, Yijie, Reinstadler, Bryn, Nomburg, Jason, Sommermann, Thomas, Cahir-McFarland, Ellen, Gygi, Steven P., Mootha, Vamsi K., Weekes, Michael P., Gewurz, Benjamin E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720460/
https://ncbi.nlm.nih.gov/pubmed/31257153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.06.003
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