H19-Dependent Transcriptional Regulation of β3 and β4 Integrins Upon Estrogen and Hypoxia Favors Metastatic Potential in Prostate Cancer

Estrogen and hypoxia promote an aggressive phenotype in prostate cancer (PCa), driving transcription of progression-associated genes. Here, we molecularly dissect the contribution of long non-coding RNA H19 to PCa metastatic potential under combined stimuli, a topic largely uncovered. The effects of...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Bacci, Lorenza, Aiello, Aurora, Ripoli, Cristian, Loria, Rossella, Pugliese, Dario, Pierconti, Francesco, Rotili, Dante, Strigari, Lidia, Pinto, Francesco, Bassi, Pier Francesco, Mai, Antonello, Grassi, Claudio, Pontecorvi, Alfredo, Falcioni, Rita, Farsetti, Antonella, Nanni, Simona
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720303/
https://ncbi.nlm.nih.gov/pubmed/31426484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20164012
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