T-Cell Deletion of MyD88 Connects IL17 and IκBζ to RAS Oncogenesis

Cancer development requires a favorable tissue microenvironment. By deleting Myd88 in keratinocytes or specific bone marrow subpopulations in oncogenic RAS-mediated skin carcinogenesis, we show that IL17 from infiltrating T cells and IκBζ signaling in keratinocytes are essential to produce a permiss...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Cataisson, Christophe, Salcedo, Rosalba, Michalowski, Aleksandra M., Klosterman, Mary, Naik, Shruti, Li, Luowei, Pan, Michelle J., Sweet, Amalia, Chen, Jin-Qiu, Kostecka, Laurie G., Karwan, Megan, Smith, Loretta, Dai, Ren-Ming, Stewart, C. Andrew, Lyakh, Lyudmila, Hsieh, Wang-Ting, Khan, Asra, Yang, Howard, Lee, Maxwell, Trinchieri, Giorgio, Yuspa, Stuart H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720116/
https://ncbi.nlm.nih.gov/pubmed/31164412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-19-0227
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados