Carcinogenic effect of potassium octatitanate (POT) fibers in the lung and pleura of male Fischer 344 rats after intrapulmonary administration

BACKGROUND: Potassium octatitanate fibers (K(2)O•8TiO(2), POT fibers) are used as an asbestos substitute. Their physical characteristics suggest that respirable POT fibers are likely to be carcinogenic in the lung and pleura. However, previous 2-year inhalation studies reported that respired POT fib...

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Udgivet i:Part Fibre Toxicol
Main Authors: Abdelgied, Mohamed, El-Gazzar, Ahmed M., Alexander, William T., Numano, Takamasa, Iigou, Masaaki, Naiki-Ito, Aya, Takase, Hiroshi, Hirose, Akihiko, Taquahashi, Yuhji, Kanno, Jun, Abdelhamid, Mona, Abdou, Khaled Abbas, Takahashi, Satoru, Alexander, David B., Tsuda, Hiroyuki
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6720102/
https://ncbi.nlm.nih.gov/pubmed/31477126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12989-019-0316-2
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