IL-4 Augments IL-31/IL-31 Receptor Alpha Interaction Leading to Enhanced Ccl 17 and Ccl 22 Production in Dendritic Cells: Implications for Atopic Dermatitis

Severe pruritus is a characteristic feature of atopic dermatitis (AD) and is closely related to its activity. Recent studies have shown that IL-31 is a key determinant of pruritus in AD. Anti-IL-31 receptor alpha (IL-31RA) antibody treatment has also been reported to improve pruritus clinically, sub...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Miake, Sho, Tsuji, Gaku, Takemura, Masaki, Hashimoto-Hachiya, Akiko, Vu, Yen Hai, Furue, Masutaka, Nakahara, Takeshi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719908/
https://ncbi.nlm.nih.gov/pubmed/31434203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20164053
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