Single-cell analysis of cardiogenesis reveals basis for organ level developmental defects

Organogenesis involves integration of myriad cell types, and dysregulation of cellular gene networks results in birth defects, affecting 5 per cent of live births. Congenital heart defects (CHD) are the most common malformations and result from disruption of discrete subsets of cardiac progenitor ce...

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Udgivet i:Nature
Main Authors: de Soysa, T. Yvanka, Ranade, Sanjeev S., Okawa, Satoshi, Ravichandran, Srikanth, Huang, Yu, Salunga, Hazel T., Schricker, Amelia, Del Sol, Antonio, Gifford, Casey A., Srivastava, Deepak
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719697/
https://ncbi.nlm.nih.gov/pubmed/31341279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-019-1414-x
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