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Clinical Pharmacokinetics and Pharmacodynamics of Nintedanib

Nintedanib is an oral, small-molecule tyrosine kinase inhibitor approved for the treatment of idiopathic pulmonary fibrosis and patients with advanced non-small cell cancer of adenocarcinoma tumour histology. Nintedanib competitively binds to the kinase domains of vascular endothelial growth factor...

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Detalhes bibliográficos
Publicado no:Clin Pharmacokinet
Main Authors: Wind, Sven, Schmid, Ulrike, Freiwald, Matthias, Marzin, Kristell, Lotz, Ralf, Ebner, Thomas, Stopfer, Peter, Dallinger, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719436/
https://ncbi.nlm.nih.gov/pubmed/31016670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40262-019-00766-0
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