Cardiac contractile dysfunction and protein kinase C–mediated myofilament phosphorylation in disease and aging

Increases in protein kinase C (PKC) are associated with diminished cardiac function, but the contribution of downstream myofilament phosphorylation is debated in human and animal models of heart failure. The current experiments evaluated PKC isoform expression, downstream cardiac troponin I (cTnI) S...

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Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Ravichandran, Vani S., Patel, Himanshu J., Pagani, Francis D., Westfall, Margaret V.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719401/
https://ncbi.nlm.nih.gov/pubmed/31366607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201912353
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