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In Vivo Cardiac Myosin Binding Protein C Gene Transfer Rescues Myofilament Contractile Dysfunction in Cardiac Myosin Binding Protein C Null Mice

BACKGROUND: Decreased expression of cardiac myosin binding protein C (cMyBPC) in the heart has been implicated as a consequence of mutations in cMyBPC that lead to abnormal contractile function at the myofilament level, thereby contributing to the development of hypertrophic cardiomyopathy in humans...

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Bibliografiset tiedot
Julkaisussa:Circ Heart Fail
Päätekijät: Merkulov, Sergei, Chen, Xiaoqin, Chandler, Margaret P., Stelzer, Julian E.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4860813/
https://ncbi.nlm.nih.gov/pubmed/22855556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCHEARTFAILURE.112.968941
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