Maintenance and enhancement of human PBSC engraftment after ex vivo culture via an HDACi/SALL4 axis (3465)

Currently, there is a growing need for culturing hematopoietic stem/progenitor cells (HSPCs) in vitro for various clinical applications including gene therapy. Compared to cord blood (CB) CD34(+) HSPCs, it is more challenging to maintain or expand peripheral blood mobilized stem/progenitor cell (PBS...

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Udgivet i:Exp Hematol
Main Authors: Tatetsu, Hiro, Gao, Chong, Armant, Myriam, Wang, Fei, Ueno, Shikiko, Tian, Xi, Federation, Alex, Qi, Jun, Bradner, James, Tenen, Daniel G., Chai, Li
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719293/
https://ncbi.nlm.nih.gov/pubmed/31260717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2019.06.473
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