Tetracycline Analogs Inhibit Osteoclast Differentiation by Suppressing MMP-9-Mediated Histone H3 Cleavage

Osteoporosis is a common disorder of bone remodeling, caused by the imbalance between bone resorption by osteoclasts and bone formation by osteoblasts. Recently, we reported that matrix metalloproteinase-9 (MMP-9)-dependent histone H3 proteolysis is a key event for proficient osteoclast formation. A...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Kim, Yeojin, Kim, Jinman, Lee, Hyerim, Shin, Woo-Ri, Lee, Sheunghun, Lee, Jisu, Park, Jae-Il, Jhun, Byung Hak, Kim, Yang-Hoon, Yi, Sun-Ju, Kim, Kyunghwan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2019
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6719029/
https://ncbi.nlm.nih.gov/pubmed/31430857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20164038
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