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Chondrocyte‐like nested cells in the aged intervertebral disc are late‐stage nucleus pulposus cells

Aging is a major risk factor of intervertebral disc degeneration and a leading cause of back pain. Pathological changes associated with disc degeneration include the absence of large, vacuolated and reticular‐shaped nucleus pulposus cells, and appearance of smaller cells nested in lacunae. These sma...

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Détails bibliographiques
Publié dans:Aging Cell
Auteurs principaux: Mohanty, Sarthak, Pinelli, Robert, Pricop, Paul, Albert, Todd J., Dahia, Chitra Lekha
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718620/
https://ncbi.nlm.nih.gov/pubmed/31290579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13006
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