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Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes
Werner Syndrome (WS) is an adult‐onset segmental progeroid syndrome. Bisulfite pyrosequencing of repetitive DNA families revealed comparable blood DNA methylation levels between classical (18 WRN‐mutant) or atypical WS (3 LMNA‐mutant and 3 POLD1‐mutant) patients and age‐ and sex‐matched controls. WS...
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| Pubblicato in: | Aging Cell |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6718529/ https://ncbi.nlm.nih.gov/pubmed/31259468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12995 |
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