Rag1 immunodeficiency‐induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress

In mammals, recombination activating gene 1 (RAG1) plays a crucial role in adaptive immunity, generating a vast range of immunoglobulins. Rag1 (−/−) zebrafish (Danio rerio) are viable and reach adulthood without obvious signs of infectious disease in standard nonsterile conditions, suggesting that i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Novoa, Beatriz, Pereiro, Patricia, López‐Muñoz, Azucena, Varela, Mónica, Forn‐Cuní, Gabriel, Anchelin, Monique, Dios, Sonia, Romero, Alejandro, Martinez‐López, Alicia, Medina‐Gali, Regla María, Collado, Manuel, Coll, Julio, Estepa, Amparo, Cayuela, María Luisa, Mulero, Victoriano, Figueras, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718522/
https://ncbi.nlm.nih.gov/pubmed/31348603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.13020
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados