Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk

AT-1/SLC33A1 is a key member of the endoplasmic reticulum (ER) acetylation machinery, transporting acetyl-CoA from the cytosol into the ER lumen where acetyl-CoA serves as the acetyl-group donor for Nε-lysine acetylation. Dysfunctional ER acetylation, as caused by heterozygous or homozygous mutation...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Dieterich, Inca A., Lawton, Alexis J., Peng, Yajing, Yu, Qing, Rhoads, Timothy W., Overmyer, Katherine A., Cui, Yusi, Armstrong, Eric A., Howell, Porsha R., Burhans, Maggie S., Li, Lingjun, Denu, John M., Coon, Joshua J., Anderson, Rozalyn M., Puglielli, Luigi
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6718414/
https://ncbi.nlm.nih.gov/pubmed/31477734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11945-9
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